Bootstrap is a toolkit from Twitter designed to kickstart development of webapps and sites. It includes base CSS and HTML for typography, forms, buttons, tables, grids, navigation, and more.
Typically I’m not a huge fan of development frameworks like this one, but digging into it there seems to be quite a few things to learn. Another framework worth looking into is the responsive Skeleton that comes from one of Twitter’s designers Dave Gamache (also on Tumblr).